Mirapex

Mirapex Attorneys

Mirapex (pramipexole) is used to treat Parkinson’s disease and restless leg syndrome (RLS). It has been linked to impulse control disorders, including compulsive gambling. On September 19, 2012, the U.S. Food and Drug Administration (FDA) announced and ongoing safety review to determine if Mirapex increases the risk of heart failure.

Mirapex Uses and how it Works

Mirapex is a dopamine receptor agonist, commonly referred to simply as a “dopamine agonist”. Dopamine agonists mimic the effects of dopamine by activating dopamine receptors. Dopamine is a neurotransmitter which is naturally occurring.

Dopamine plays many important roles in the brain and the body. Among those are its role in the reward system in the brain and a role in controlling body movements.

People with Parkinson’s disease do not produce enough dopamine. It is believed that decreased dopamine activity is also involved in RLS.

Mirapex may also be prescribed off-label to treat:

  • Bipolar disorder
  • Treatment-resistant depression
  • Sexual dysfunction in patients taking SSRI antidepressants
  • Fibromyalgia
  • Cluster headache

Heart Failure

FDA analysis of the results of clinical trials and epidemiologic studies found that the rate of heart failure was higher with Mirapex than a placebo and that there may be an increased risk of new onset of heart failure with Mirapex use.

According the FDA the risk of heart failure with Mirapex use needs to be investigated further before the agency can decide if it feels there is truly an increased risk of heart failure when using the drug.

Impulse Control Disorders

Mirapex can cause impulse control disorders including:

  • Gambling addiction
  • Compulsive shopping
  • Binge eating
  • Hyper-sexuality

In July, 2005, a Mayo Clinic study, published in the Archives of Neurology gave details of 11 Parkinson’s patients who developed gambling problems while taking Mirapex or similar drugs between 2002 and 2004. After the study was published Mayo doctor discovered 14 more of their patients with the same problem.

Those who suffer from impulse control disorders while taking Mirapex say that the problem goes away when they stop taking the drug.

Mirapex impulse control disorder victims are often reluctant to come forward because of the stigma associated with the disorders. Those who develop gambling addictions often lose their homes, jobs, and families, fall into deep depression and can even be driven to suicide.

If you have been harmed by Mirapex, or if you have lost a loved one to this dangerous medication, you may be entitled to compensation. Please talk to a Mirapex injury attorney in your area right away.