Actos

Actos Lawsuit

Actos (pioglitazone) is used to control the symptoms of Type 2 diabetes. It is often prescribed in place of Avandia (rosiglitazone), due to restrictions on Avandia use, but Actos is just as dangerous for the heart. Actos has been linked to many dangerous and deadly side effects including heart failure and death. If you have taken Actos and suffered injury, you may have an Actos lawsuit.

Actos Uses

Type 2 diabetes is insulin resistance. Your body can produce enough insulin, but does not use it properly. Actos is used to treat the symptoms of Type 2 diabetes and is intended to improve your body’s ability to use insulin. It does not reverse the condition.Actos  does not increase insulin levels and  is not used to treat Type 1 diabetes.

Heart Attack, Heart Failure, and Death

Actos can cause congestive heart failure, heat attack, and death. It was once thought to be safer for the heart than Avandia, and the U.S. Food and Drug Administration (FDA) placed tight restrictions on Avandia use, including the requirement that Actos be used instead when possible.

However, a study published in 2010 found that both drugs carry the same risk of causing heart attack, heart failure, and death.

Bladder Cancer

The FDA was aware of a potential bladder cancer risk when it approved Actos. The agency required maker of Actos, Tadeka, to include a warning on the Actos label and conduct a ten year study to determine if Actos users had an increased risk of bladder cancer.

The FDA began its review of the first half of the bladder cancer study in 2010, and concluded that the risk of bladder cancer was significantly higher after using the drug for two years.

France has suspended Actos use and Germany no longer allows Actos to be prescribed to new patients. A study published in the British Medical Journal (BMJ) on May 31, 2012, found that using Actos for any amount of time increases the risk of bladder cancer by 83% and using it for more than two years doubles the risk of developing bladder cancer.

Bone Fractures

Actos increases the risk of bone fracture in post-menopausal women. When taken in combination with loop diuretics, it increases the risk of bone fracture in men.

Liver Damage

Before starting Actos use, patients must have their liver enzymes checked, and while taking the drug must continue testing on a regular basis. Actos is known to cause liver problems including:

  • Elevated liver enzymes
  • Inflammation of the liver
  • Hepatitis
  • Liver failure

Kidney Damage

Actos can cause a severe kidney damage, most commonly a dangerous condition called rhabdomyolysis. In rhabdomyolysis, muscle fibers breakdown rapidly, releasing a protein called myoglobin. Myoglobin can be toxic to the kidneys.

If you have been injured by Actos or another defective medication, please talk to an injury lawyer in your area right away and see if you have an Actos lawsuit.